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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM368283'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM368283
PNG
(US10227338, Example 66)
Show SMILES CN1CCN(CC1)c1cc(OC(F)F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1
Show InChI InChI=1S/C21H21ClF3N5O3S2/c1-29-4-6-30(7-5-29)18-8-13(33-21(24)25)2-3-16(18)27-17-10-15(23)19(9-14(17)22)35(31,32)28-20-11-34-12-26-20/h2-3,8-12,21,27-28H,4-7H2,1H3
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US Patent
n/an/a 160n/an/an/an/an/an/a



Daewoong Pharmaceutical Co., Ltd.

US Patent


Assay Description
In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...


US Patent US10227338 (2019)


BindingDB Entry DOI: 10.7270/Q2F47RFM
More data for this
Ligand-Target Pair