Found 5 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM50240278' TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Department Of Discovery Chemistry Merck
Curated by ChEMBL
Department Of Discovery Chemistry Merck
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells at holding potential of -60 mV incubated for 5 mins measured at 10 secs int...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Department Of Discovery Chemistry Merck
Curated by ChEMBL
Department Of Discovery Chemistry Merck
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of 50% inactivated mouse Nav1.7 expressed in HEK293 cells at holding potential of -60 mV incubated for 5 mins measured at 10 secs interval...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Department Of Discovery Chemistry Merck
Curated by ChEMBL
Department Of Discovery Chemistry Merck
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse Nav1.7 alpha expressed in HEK293 cells incubated for 5 mins measured after depolarization to 7 mV for 8s followed by 20ms pulse w...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Department Of Discovery Chemistry Merck
Curated by ChEMBL
Department Of Discovery Chemistry Merck
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human Nav1.7 alpha expressed in HEK293 cells incubated for 5 mins with 6 consecutive train pulses to -10 mV at 0.1 Hz and holding poten...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Department Of Discovery Chemistry Merck
Curated by ChEMBL
Department Of Discovery Chemistry Merck
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of mouse Nav1.7 alpha expressed in HEK293 cells incubated for 5 mins measured after hyperpolarization to -115 mV for 8s followed by 20ms p...More data for this Ligand-Target Pair
