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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM388637'
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM388637(AZD1858 MCJ001- SS | US9944618, Compound ID No. 17...)
Affinity DataKi:  0.5nMAssay Description:NET: This protocol was designed to measure inhibition of uptake by the human norepinephrine transporter. The reagents were human NET (HEK293F) cells,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM388637(AZD1858 MCJ001- SS | US9944618, Compound ID No. 17...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human NET expressed in HEK293 cells after 60 mins in presence of [3H]imipramine by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Foundation

US Patent
LigandPNGBDBM388637(AZD1858 MCJ001- SS | US9944618, Compound ID No. 17...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human NET expressed in HEK293 cells after 60 mins in presence of [3H]imipramine by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed