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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent noradrenaline transporter' and Ligand = 'BDBM50243158'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent noradrenaline transporter


(Homo sapiens (Human))
BDBM50243158
PNG
(CHEMBL487869 | cis-3-(2-methoxyphenoxy)-N,N-dimeth...)
Show SMILES COc1ccccc1O[C@H]1C[C@@H](N(C)C)c2ccccc12
Show InChI InChI=1S/C18H21NO2/c1-19(2)15-12-18(14-9-5-4-8-13(14)15)21-17-11-7-6-10-16(17)20-3/h4-11,15,18H,12H2,1-3H3/t15-,18+/m1/s1
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Similars

Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Neurocrine Biosciences Inc

Curated by ChEMBL


Assay Description
Inhibition of norepinephrine uptake at human NET in human HEK293 cells


Bioorg Med Chem Lett 18: 4224-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.057
BindingDB Entry DOI: 10.7270/Q2T154J4
More data for this
Ligand-Target Pair