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Found 1 hit Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50298610'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))
BDBM50298610
PNG
(3beta-(4-Methylthiophenyl)nortropane-2beta-carboxy...)
Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1c1ccc(SC)cc1)N2
Show InChI InChI=1S/C16H21NO2S/c1-19-16(18)15-13(9-11-5-8-14(15)17-11)10-3-6-12(20-2)7-4-10/h3-4,6-7,11,13-15,17H,5,8-9H2,1-2H3/t11?,13-,14?,15+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.190n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]paroxetine from 5-HTT


Bioorg Med Chem 17: 5126-32 (2009)


Article DOI: 10.1016/j.bmc.2009.05.052
BindingDB Entry DOI: 10.7270/Q2611186
More data for this
Ligand-Target Pair