Found 6 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM50041983' TargetSphingosine 1-phosphate receptor 1(Mus musculus (Mouse))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 0.0640nMAssay Description:Agonist activity at mouse S1P1 receptor assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0500nMAssay Description:Agonist activity at rat S1P1 receptor assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 0.0210nMAssay Description:Agonist activity at human S1P1 receptor assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0580nMAssay Description:Agonist activity at monkey S1P1 receptor assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 0.620nMAssay Description:Agonist activity at human S1P1 receptor by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Canis lupus familiaris)
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 0.0490nMAssay Description:Agonist activity at dog S1P1 receptor assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
