Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Sterol O-acyltransferase 1' and Ligand = 'BDBM182847'
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kowa

Curated by ChEMBL
LigandPNGBDBM182847(US9149492, K-604)
Affinity DataIC50:  26nMAssay Description:Inhibition of ACAT in human J774A.1 cells assessed as reduction in esterified-cholesterol accumulation after 18 hrs in presence of 25-hydroxycholeste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kowa

Curated by ChEMBL
LigandPNGBDBM182847(US9149492, K-604)
Affinity DataIC50:  450nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kowa

Curated by ChEMBL
LigandPNGBDBM182847(US9149492, K-604)
Affinity DataIC50:  450nMAssay Description:Inhibition of human ACAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed