Found 2 Enz. Inhib. hit(s) with Target = 'Stimulator of interferon genes protein [139-379,H232R]' and Ligand = 'BDBM501204' TargetStimulator of interferon genes protein [139-379,H232R](Homo sapiens (Human))
Janssen Biotech
US Patent
Janssen Biotech
US Patent
Affinity DataIC50: <10nMAssay Description:The human STING SPA binding assay measures displacement of tritium labeled 2′,3′cGAMP (cyclic (guanosine-(2′→5′)-monoph...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [139-379,H232R](Homo sapiens (Human))
Janssen Biotech
US Patent
Janssen Biotech
US Patent
Affinity DataEC50: 19nMAssay Description:Agonism of the human STING pathway is assessed in THP1-ISG cells (Invivogen, cat #thp-isg) derived from human THP1 monocyte cell line by stable integ...More data for this Ligand-Target Pair
