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Found 2 Enz. Inhib. hit(s) with Target = 'Stromelysin-1' and Ligand = 'BDBM50149219'
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50149219(3-(3'-Cyanomethyl-biphenyl-4-yloxy)-N-hydroxy-prop...)
Affinity DataIC50:  15nMAssay Description:Inhibition of MMP3 (unknown origin) using Ac-Pro-Leu-Gly-[2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt as substrate incubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50149219(3-(3'-Cyanomethyl-biphenyl-4-yloxy)-N-hydroxy-prop...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed