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Found 2 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50398245'
TargetToll-like receptor 8(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50398245(CHEMBL512901 | CL-075)
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at TLR8 in human cryopreserved PBMC assessed as inhibition of IL-12p40 production measured after 24 hrsMore data for this Ligand-Target Pair
TargetToll-like receptor 8(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50398245(CHEMBL512901 | CL-075)
Affinity DataEC50:  1.32E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NF-kappaB activity by measuring extracellular secreted alkaline pho...More data for this Ligand-Target Pair