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Found 2 Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50533637'
TargetToll-like receptor 8(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533637(CHEMBL4522643)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NF-kappaB activity by secreted alkaline phosphatase reporter gene a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 8(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533637(CHEMBL4522643)
Affinity DataEC50:  9.26E+3nMAssay Description:Agonist activity at TLR8 in human PBMC assessed as increase in TNF-alpha production after 16 hrs by immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed