Found 11 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM2579' TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 17.2nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 18.1nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 22.1nMAssay Description:1H-pyrrolo[2,3-b]pyridine, 1H-pyrazolo[3,4-b]pyridine and 5H-pyrrolo[2,3-b]pyrazine series of compounds exhibited over >100 fold selective against Ja...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 23.3nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of BTK (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortexMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataKd: 210nMAssay Description:Binding constant for BTK kinase domainMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataKd: 710nMAssay Description:Average Binding Constant for BTK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataKd: 210nMAssay Description:Binding constant for full-length BTKMore data for this Ligand-Target Pair
