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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ITK/TSK' and Ligand = 'BDBM50443189'
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50443189(CHEMBL3086327)
Affinity DataKi:  5.30nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50443189(CHEMBL3086327)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed