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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM116319'
Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Genentech
US Patent
Ligand
BDBM116319
(US8637526, 343)
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Affinity Data
Ki: 29.9nM
pH: 7.2
Assay Description:
To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 1.5 nM JAK1, 0.2 nM pu...
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Ligand Info
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