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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332811'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))
BDBM332811
PNG
(US10196390, Compound I-83)
Show SMILES Fc1cccc(c1-c1nc2CNC(=O)c2c(Nc2ccc(CC(=O)NC3CCNCC3)cc2)n1)C(F)(F)F
Show InChI InChI=1S/C26H24F4N6O2/c27-18-3-1-2-17(26(28,29)30)21(18)23-35-19-13-32-25(38)22(19)24(36-23)34-15-6-4-14(5-7-15)12-20(37)33-16-8-10-31-11-9-16/h1-7,16,31H,8-13H2,(H,32,38)(H,33,37)(H,34,35,36)
PDB

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PC cid
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US Patent
550n/an/an/an/an/an/an/an/a



Nimbus Lakshmi, Inc.

US Patent




US Patent US10196390 (2019)


BindingDB Entry DOI: 10.7270/Q22809Q4
More data for this
Ligand-Target Pair