Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50305155'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305155(3-fluoro-4-{8,12,14,16-tetraazatetracyclo[8.6.1.0^...)
Affinity DataKi:  1nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305155(3-fluoro-4-{8,12,14,16-tetraazatetracyclo[8.6.1.0^...)
Affinity DataIC50:  200nMAssay Description:Inhibition of JAK2 in granulocyte macrophage colony stimulating factor-stimulated human TF1 cells assessed as phosphorylation of STAT5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed