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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM116319'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM116319(US8637526, 343)
Affinity DataKi:  28.6nM ΔG°:  -42.6kJ/molepH: 7.2 T: 2°CAssay Description:To determine inhibition constants (Ki), compounds were diluted serially in DMSO and added to 50 uL kinase reactions containing 5 nM purified JAK3 enz...More data for this Ligand-Target Pair
In DepthDetails US Patent