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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50132443'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132443(4-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132443(4-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataIC50:  12nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Rattus norvegicus)
Rigel

Curated by ChEMBL
LigandPNGBDBM50132443(4-{5-Methoxy-3-[2-oxo-5-sulfamoyl-1,2-dihydro-indo...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of SYK in rat RBL2H3 cells assessed as reduction in DNP-BSA-stimulated Fcepsilon receptor 1-mediated 5-HT releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed