Found 12 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM50391109' TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Shanghai Jiao Tong University (Sjtu)
Curated by ChEMBL
Shanghai Jiao Tong University (Sjtu)
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrate after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Shanghai Jiao Tong University (Sjtu)
Curated by ChEMBL
Shanghai Jiao Tong University (Sjtu)
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant GST-tagged SHP2 (catalytic domain 1116 to 2162 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as subst...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Jiangnan University
Curated by ChEMBL
Jiangnan University
Curated by ChEMBL
Affinity DataIC50: 7.43E+3nMAssay Description:Inhibition of SHP2 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Shanghai Jiao Tong University (Sjtu)
Curated by ChEMBL
Shanghai Jiao Tong University (Sjtu)
Curated by ChEMBL
Affinity DataIC50: 7.43E+3nMAssay Description:Inhibition of SHP2 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Shanghai Jiao Tong University (Sjtu)
Curated by ChEMBL
Shanghai Jiao Tong University (Sjtu)
Curated by ChEMBL
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Jiangnan University
Curated by ChEMBL
Jiangnan University
Curated by ChEMBL
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Jiangnan University
Curated by ChEMBL
Jiangnan University
Curated by ChEMBL
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of human GST-tagged SHP2 (1116 to 2162 residues) expressed in Escherichia coli BL21-CondenPlus (DE3) using pNNP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Jiangnan University
Curated by ChEMBL
Jiangnan University
Curated by ChEMBL
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Jiangnan University
Curated by ChEMBL
Jiangnan University
Curated by ChEMBL
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Shanghai Jiao Tong University (Sjtu)
Curated by ChEMBL
Shanghai Jiao Tong University (Sjtu)
Curated by ChEMBL
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Jiangnan University
Curated by ChEMBL
Jiangnan University
Curated by ChEMBL
Affinity DataIC50: 3.47E+4nMAssay Description:IC50 values were determined by pNPP assay.More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Jiangnan University
Curated by ChEMBL
Jiangnan University
Curated by ChEMBL
Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
