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Found 1 hit Enz. Inhib. hit(s) with Target = 'Urokinase-type plasminogen activator' and Ligand = 'BDBM13946'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM13946
PNG
(APC-13417 | [amino({2-[(phenylcarbamoyl)amino]-1H-...)
Show SMILES NC(=[NH2+])c1ccc2nc(NC(=O)Nc3ccccc3)[nH]c2c1
Show InChI InChI=1S/C15H14N6O/c16-13(17)9-6-7-11-12(8-9)20-14(19-11)21-15(22)18-10-4-2-1-3-5-10/h1-8H,(H3,16,17)(H3,18,19,20,21,22)/p+1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
3.00E+4n/an/an/an/an/an/an/an/a



Axys Pharmaceuticals Corporation



Assay Description
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...


J Mol Biol 307: 1451-86 (2001)


Article DOI: 10.1006/jmbi.2001.4516
BindingDB Entry DOI: 10.7270/Q2FX77PG
More data for this
Ligand-Target Pair