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Found 3 Enz. Inhib. hit(s) with Target = 'Urokinase-type plasminogen activator' and Ligand = 'BDBM14149'
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14149(6-fluoro-2-(2-hydroxy-3-{[(1S,2S)-2-methylcyclohex...)
Affinity DataKi:  11nM ΔG°:  -45.0kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14149(6-fluoro-2-(2-hydroxy-3-{[(1S,2S)-2-methylcyclohex...)
Affinity DataKi:  25nM ΔG°:  -43.0kJ/molepH: 8.2 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14149(6-fluoro-2-(2-hydroxy-3-{[(1S,2S)-2-methylcyclohex...)
Affinity DataKi:  140nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair