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Found 5 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 1' and Ligand = 'BDBM9504'
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM9504(2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...)
Affinity DataIC50:  15nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM9504(2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...)
Affinity DataIC50:  160nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM9504(2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...)
Affinity DataIC50:  160nMAssay Description:Inhibitory activity against VEGFR-1 using 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM9504(2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...)
Affinity DataIC50:  160nMAssay Description:Inhibition of VEGFR1 by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM9504(2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...)
Affinity DataIC50:  170nMpH: 7.5 T: 2°CAssay Description:In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed