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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-gated L-type calcium channel' and Ligand = 'BDBM50000342'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated L-type calcium channel


(Homo sapiens (Human))
BDBM50000342
PNG
(Acetic acid 7-chloro-1-(2-dimethylamino-ethyl)-4-(...)
Show SMILES COc1ccccc1[C@@H]1Cc2cc(Cl)ccc2N(CCN(C)C)C(=O)[C@@H]1OC(C)=O
Show InChI InChI=1S/C23H27ClN2O4/c1-15(27)30-22-19(18-7-5-6-8-21(18)29-4)14-16-13-17(24)9-10-20(16)26(23(22)28)12-11-25(2)3/h5-10,13,19,22H,11-12,14H2,1-4H3/t19-,22+/m0/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/a 5.80E+3n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro ability to displace the specific binding of [3H]-diltiazem to diltiazem receptor in guinea pig skeletal muscle.


J Med Chem 35: 780-93 (1992)


Article DOI: 10.1021/jm00082a020
BindingDB Entry DOI: 10.7270/Q2K64H14
More data for this
Ligand-Target Pair