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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-gated L-type calcium channel' and Ligand = 'BDBM50000362'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated L-type calcium channel


(Homo sapiens (Human))
BDBM50000362
PNG
(Acetic acid 1-(2-dimethylamino-ethyl)-4-(4-methoxy...)
Show SMILES CNC(=O)Oc1ccc2N(CCN(C)C)C(=O)[C@H](OC(C)=O)[C@@H](Cc2c1)c1ccc(OC)cc1
Show InChI InChI=1S/C25H31N3O6/c1-16(29)33-23-21(17-6-8-19(32-5)9-7-17)15-18-14-20(34-25(31)26-2)10-11-22(18)28(24(23)30)13-12-27(3)4/h6-11,14,21,23H,12-13,15H2,1-5H3,(H,26,31)/t21-,23+/m0/s1
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Similars

Article
PubMed
n/an/an/a 1.20E+4n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro ability to displace the specific binding of [3H]-diltiazem to diltiazem receptor in guinea pig skeletal muscle.


J Med Chem 35: 780-93 (1992)


Article DOI: 10.1021/jm00082a020
BindingDB Entry DOI: 10.7270/Q2K64H14
More data for this
Ligand-Target Pair