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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-gated L-type calcium channel' and Ligand = 'BDBM50000373'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated L-type calcium channel


(Homo sapiens (Human))
BDBM50000373
PNG
(Acetic acid 1-[2-(allyl-methyl-amino)-ethyl]-4-(4-...)
Show SMILES COc1ccc(cc1)[C@@H]1Cc2c(cccc2C(F)(F)F)N(CCN(C)CC=C)C(=O)[C@@H]1OC(C)=O
Show InChI InChI=1S/C26H29F3N2O4/c1-5-13-30(3)14-15-31-23-8-6-7-22(26(27,28)29)21(23)16-20(24(25(31)33)35-17(2)32)18-9-11-19(34-4)12-10-18/h5-12,20,24H,1,13-16H2,2-4H3/t20-,24+/m0/s1
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Similars

Article
PubMed
n/an/an/a 420n/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro ability to displace the specific binding of [3H]-diltiazem to diltiazem receptor in guinea pig skeletal muscle.


J Med Chem 35: 780-93 (1992)


Article DOI: 10.1021/jm00082a020
BindingDB Entry DOI: 10.7270/Q2K64H14
More data for this
Ligand-Target Pair