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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-gated potassium channel subunit Kv1.5' and Ligand = 'BDBM50194520'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv1.5


(Homo sapiens (Human))
BDBM50194520
PNG
(CHEMBL385920 | N1,N1-diisopropyl-3-phenyl-N5-((4-p...)
Show SMILES CC(C)N(C(C)C)C(=O)C(C(CC(=O)NCC1CN(CCO1)c1ccccc1)c1ccccc1)c1cccnc1
Show InChI InChI=1S/C33H42N4O3/c1-24(2)37(25(3)4)33(39)32(27-14-11-17-34-21-27)30(26-12-7-5-8-13-26)20-31(38)35-22-29-23-36(18-19-40-29)28-15-9-6-10-16-28/h5-17,21,24-25,29-30,32H,18-20,22-23H2,1-4H3,(H,35,38)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 3.38E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5


Bioorg Med Chem Lett 16: 5897-901 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.054
BindingDB Entry DOI: 10.7270/Q2Z60NP6
More data for this
Ligand-Target Pair