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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-gated potassium channel subunit Kv1.5' and Ligand = 'BDBM50194543'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv1.5


(Homo sapiens (Human))
BDBM50194543
PNG
(CHEMBL384706 | N1,N1-diisopropyl-N5-phenethyl-3-ph...)
Show SMILES CC(C)N(C(C)C)C(=O)C(C(CC(=O)NCCc1ccccc1)c1ccccc1)c1cccnc1
Show InChI InChI=1S/C30H37N3O2/c1-22(2)33(23(3)4)30(35)29(26-16-11-18-31-21-26)27(25-14-9-6-10-15-25)20-28(34)32-19-17-24-12-7-5-8-13-24/h5-16,18,21-23,27,29H,17,19-20H2,1-4H3,(H,32,34)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 410n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5


Bioorg Med Chem Lett 16: 5897-901 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.054
BindingDB Entry DOI: 10.7270/Q2Z60NP6
More data for this
Ligand-Target Pair