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Found 1 Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM208975'
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM208975(US9266881, 13-6)
Affinity DataKi:  546nM ΔG°:  -35.7kJ/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAPĀ® FP kit supplied by Molecular Devices, Sunn...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent