Found 2 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50183808' TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human GST-PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Ability to block TNFalpha release through inhibition of PDE4 in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair
