BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'h-v1b' and Ligand = 'BDBM316350'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
h-v1b


(Homo sapiens (Human))
BDBM316350
PNG
(US9617226, Example 31 | cis-2-[2-(3-Chlorophenyl)-...)
Show SMILES CC(C)NC(=O)Cn1c(nc2ccc(cc2c1=O)[C@@H]1C[C@H](CN2CC3(COC3)C2)C1)-c1cccc(Cl)c1
Show InChI InChI=1S/C29H33ClN4O3/c1-18(2)31-26(35)13-34-27(21-4-3-5-23(30)10-21)32-25-7-6-20(11-24(25)28(34)36)22-8-19(9-22)12-33-14-29(15-33)16-37-17-29/h3-7,10-11,18-19,22H,8-9,12-17H2,1-2H3,(H,31,35)/t19-,22+
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
5.5n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG

US Patent


Assay Description
The binding assay was carried out by the method based on that of Tahara et al. (Tahara A et al., Brit. J. Pharmacol. 125, 1463-1470 (1998)).The incub...


US Patent US9617226 (2017)


Article DOI: 10.1016/j.bmcl.2008.11.034
More data for this
Ligand-Target Pair