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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50112562   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50112562
PNG
(CHEMBL27777 | N-(2-Hydroxy-1,1-dimethyl-ethyl)-N'-...)
Show SMILES COc1cc(NC(=O)C(=O)NC(C)(C)CO)ccc1-c1cnco1
Show InChI InChI=1S/C16H19N3O5/c1-16(2,8-20)19-15(22)14(21)18-10-4-5-11(12(6-10)23-3)13-7-17-9-24-13/h4-7,9,20H,8H2,1-3H3,(H,18,21)(H,19,22)
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MMDB

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Article
PubMed
n/an/a 19n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 1323-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00132-4
BindingDB Entry DOI: 10.7270/Q2NG4PX7
More data for this
Ligand-Target Pair