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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50112563   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50112563
PNG
(CHEMBL25681 | N-(3-Methoxy-4-oxazol-5-yl-phenyl)-N...)
Show SMILES COc1cc(NC(=O)C(=O)NC(C)(C)c2ccccc2)ccc1-c1cnco1
Show InChI InChI=1S/C21H21N3O4/c1-21(2,14-7-5-4-6-8-14)24-20(26)19(25)23-15-9-10-16(17(11-15)27-3)18-12-22-13-28-18/h4-13H,1-3H3,(H,23,25)(H,24,26)
PDB
MMDB

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Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 1323-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00132-4
BindingDB Entry DOI: 10.7270/Q2NG4PX7
More data for this
Ligand-Target Pair