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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50112571   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50112571
PNG
(CHEMBL27985 | N-tert-Butyl-N'-(4-oxazol-5-yl-pheny...)
Show SMILES CC(C)(C)NC(=O)C(=O)Nc1ccc(cc1)-c1cnco1
Show InChI InChI=1S/C15H17N3O3/c1-15(2,3)18-14(20)13(19)17-11-6-4-10(5-7-11)12-8-16-9-21-12/h4-9H,1-3H3,(H,17,19)(H,18,20)
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Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of inosine-5'-monophosphate dehydrogenase 2.


Bioorg Med Chem Lett 13: 2059-63 (2003)


Article DOI: 10.1016/s0960-894x(03)00258-0
BindingDB Entry DOI: 10.7270/Q22Z14X1
More data for this
Ligand-Target Pair
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50112571
PNG
(CHEMBL27985 | N-tert-Butyl-N'-(4-oxazol-5-yl-pheny...)
Show SMILES CC(C)(C)NC(=O)C(=O)Nc1ccc(cc1)-c1cnco1
Show InChI InChI=1S/C15H17N3O3/c1-15(2,3)18-14(20)13(19)17-11-6-4-10(5-7-11)12-8-16-9-21-12/h4-9H,1-3H3,(H,17,19)(H,18,20)
PDB
MMDB

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KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 1323-6 (2002)


Article DOI: 10.1016/s0960-894x(02)00132-4
BindingDB Entry DOI: 10.7270/Q2NG4PX7
More data for this
Ligand-Target Pair