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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50116128   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50116128
PNG
(6-((S)-2-Methoxymethyl-pyrrolidin-1-yl)-N-(3-metho...)
Show SMILES CNc1nc(Nc2ccc(-c3cnco3)c(OC)c2)nc(n1)N1CCC[C@H]1COC
Show InChI InChI=1S/C20H25N7O3/c1-21-18-24-19(26-20(25-18)27-8-4-5-14(27)11-28-2)23-13-6-7-15(16(9-13)29-3)17-10-22-12-30-17/h6-7,9-10,12,14H,4-5,8,11H2,1-3H3,(H2,21,23,24,25,26)/t14-/m0/s1
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Article
PubMed
n/an/a 390n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 2137-40 (2002)


Article DOI: 10.1016/s0960-894x(02)00351-7
BindingDB Entry DOI: 10.7270/Q2NZ86Z7
More data for this
Ligand-Target Pair