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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50116129   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50116129
PNG
(CHEMBL307547 | N*3*-(3-Methoxy-4-oxazol-5-yl-pheny...)
Show SMILES COc1cc(Nc2nc(N)n(n2)-c2ccccc2)ccc1-c1cnco1
Show InChI InChI=1S/C18H16N6O2/c1-25-15-9-12(7-8-14(15)16-10-20-11-26-16)21-18-22-17(19)24(23-18)13-5-3-2-4-6-13/h2-11H,1H3,(H3,19,21,22,23)
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n/an/a 150n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)


Bioorg Med Chem Lett 12: 3125-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00641-8
BindingDB Entry DOI: 10.7270/Q2959GXF
More data for this
Ligand-Target Pair
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50116129
PNG
(CHEMBL307547 | N*3*-(3-Methoxy-4-oxazol-5-yl-pheny...)
Show SMILES COc1cc(Nc2nc(N)n(n2)-c2ccccc2)ccc1-c1cnco1
Show InChI InChI=1S/C18H16N6O2/c1-25-15-9-12(7-8-14(15)16-10-20-11-26-16)21-18-22-17(19)24(23-18)13-5-3-2-4-6-13/h2-11H,1H3,(H3,19,21,22,23)
PDB
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Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 2137-40 (2002)


Article DOI: 10.1016/s0960-894x(02)00351-7
BindingDB Entry DOI: 10.7270/Q2NZ86Z7
More data for this
Ligand-Target Pair