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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50116132   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50116132
PNG
((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-methoxy-6-phen...)
Show SMILES COc1nc(Nc2ccc(-c3cnco3)c(OC)c2)nc(n1)-c1ccccc1
Show InChI InChI=1S/C20H17N5O3/c1-26-16-10-14(8-9-15(16)17-11-21-12-28-17)22-19-23-18(24-20(25-19)27-2)13-6-4-3-5-7-13/h3-12H,1-2H3,(H,22,23,24,25)
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Article
PubMed
n/an/a 41n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)


Bioorg Med Chem Lett 12: 3125-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00641-8
BindingDB Entry DOI: 10.7270/Q2959GXF
More data for this
Ligand-Target Pair
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50116132
PNG
((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-methoxy-6-phen...)
Show SMILES COc1nc(Nc2ccc(-c3cnco3)c(OC)c2)nc(n1)-c1ccccc1
Show InChI InChI=1S/C20H17N5O3/c1-26-16-10-14(8-9-15(16)17-11-21-12-28-17)22-19-23-18(24-20(25-19)27-2)13-6-4-3-5-7-13/h3-12H,1-2H3,(H,22,23,24,25)
PDB
MMDB

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UniProtKB/SwissProt
UniProtKB/TrEMBL

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antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 41n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 2137-40 (2002)


Article DOI: 10.1016/s0960-894x(02)00351-7
BindingDB Entry DOI: 10.7270/Q2NZ86Z7
More data for this
Ligand-Target Pair