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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50116141   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50116141
PNG
(CHEMBL305214 | N-(3-Methoxy-4-oxazol-5-yl-phenyl)-...)
Show SMILES CNc1nc(Nc2ccc(-c3cnco3)c(OC)c2)nc(n1)N1CCOCC1
Show InChI InChI=1S/C18H21N7O3/c1-19-16-22-17(24-18(23-16)25-5-7-27-8-6-25)21-12-3-4-13(14(9-12)26-2)15-10-20-11-28-15/h3-4,9-11H,5-8H2,1-2H3,(H2,19,21,22,23,24)
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MMDB

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Article
PubMed
n/an/a 160n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 2137-40 (2002)


Article DOI: 10.1016/s0960-894x(02)00351-7
BindingDB Entry DOI: 10.7270/Q2NZ86Z7
More data for this
Ligand-Target Pair