BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50116145   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50116145
PNG
(4-[4-(3-Methoxy-4-oxazol-5-yl-phenylamino)-6-pheny...)
Show SMILES COc1cc(Nc2nc(NCCCC(O)=O)nc(n2)-c2ccccc2)ccc1-c1cnco1
Show InChI InChI=1S/C23H22N6O4/c1-32-18-12-16(9-10-17(18)19-13-24-14-33-19)26-23-28-21(15-6-3-2-4-7-15)27-22(29-23)25-11-5-8-20(30)31/h2-4,6-7,9-10,12-14H,5,8,11H2,1H3,(H,30,31)(H2,25,26,27,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 78n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 2137-40 (2002)


Article DOI: 10.1016/s0960-894x(02)00351-7
BindingDB Entry DOI: 10.7270/Q2NZ86Z7
More data for this
Ligand-Target Pair