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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50116146   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50116146
PNG
((4-Benzyloxy-6-phenyl-[1,3,5]triazin-2-yl)-(3-meth...)
Show SMILES COc1cc(Nc2nc(OCc3ccccc3)nc(n2)-c2ccccc2)ccc1-c1cnco1
Show InChI InChI=1S/C26H21N5O3/c1-32-22-14-20(12-13-21(22)23-15-27-17-34-23)28-25-29-24(19-10-6-3-7-11-19)30-26(31-25)33-16-18-8-4-2-5-9-18/h2-15,17H,16H2,1H3,(H,28,29,30,31)
PDB
MMDB

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Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 2137-40 (2002)


Article DOI: 10.1016/s0960-894x(02)00351-7
BindingDB Entry DOI: 10.7270/Q2NZ86Z7
More data for this
Ligand-Target Pair