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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50119017   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50119017
PNG
((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-pyridin-4...)
Show SMILES COc1cc(NC(=O)\C=C\c2ccncc2)ccc1-c1cnco1
Show InChI InChI=1S/C18H15N3O3/c1-23-16-10-14(3-4-15(16)17-11-20-12-24-17)21-18(22)5-2-13-6-8-19-9-7-13/h2-12H,1H3,(H,21,22)/b5-2+
PDB
MMDB

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Similars

Article
PubMed
n/an/a 57n/an/an/an/an/an/a



Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibitory activity of compound was evaluated against the Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 2879-82 (2002)


Article DOI: 10.1016/s0960-894x(02)00601-7
BindingDB Entry DOI: 10.7270/Q29886B5
More data for this
Ligand-Target Pair