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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50119022   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50119022
PNG
((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-thiophen-...)
Show SMILES COc1cc(NC(=O)\C=C\c2cccs2)ccc1-c1cnco1
Show InChI InChI=1S/C17H14N2O3S/c1-21-15-9-12(4-6-14(15)16-10-18-11-22-16)19-17(20)7-5-13-3-2-8-23-13/h2-11H,1H3,(H,19,20)/b7-5+
PDB
MMDB

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Article
PubMed
n/an/a 66n/an/an/an/an/an/a



Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibitory activity of compound was evaluated against the Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 2879-82 (2002)


Article DOI: 10.1016/s0960-894x(02)00601-7
BindingDB Entry DOI: 10.7270/Q29886B5
More data for this
Ligand-Target Pair