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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50119027   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50119027
PNG
((E)-3-(4-Fluoro-2,6-dimethyl-phenyl)-N-(3-methoxy-...)
Show SMILES COc1cc(NC(=O)\C=C\c2c(C)cc(F)cc2C)ccc1-c1cnco1
Show InChI InChI=1S/C21H19FN2O3/c1-13-8-15(22)9-14(2)17(13)6-7-21(25)24-16-4-5-18(19(10-16)26-3)20-11-23-12-27-20/h4-12H,1-3H3,(H,24,25)/b7-6+
PDB
MMDB

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Article
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n/an/a 75n/an/an/an/an/an/a



Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibitory activity of compound was evaluated against the Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 2879-82 (2002)


Article DOI: 10.1016/s0960-894x(02)00601-7
BindingDB Entry DOI: 10.7270/Q29886B5
More data for this
Ligand-Target Pair