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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50119111   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50119111
PNG
(CHEMBL98904 | N''-methoxy-N-[3-methoxy-4-(1,3-oxaz...)
Show SMILES CONC(Nc1cccc(C)c1)=Nc1ccc(-c2cnco2)c(OC)c1
Show InChI InChI=1S/C19H20N4O3/c1-13-5-4-6-14(9-13)21-19(23-25-3)22-15-7-8-16(17(10-15)24-2)18-11-20-12-26-18/h4-12H,1-3H3,(H2,21,22,23)
PDB
MMDB

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Article
PubMed
n/an/a 660n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.


Bioorg Med Chem Lett 12: 2931-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00600-5
BindingDB Entry DOI: 10.7270/Q2SB454K
More data for this
Ligand-Target Pair