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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50119117   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50119117
PNG
(CHEMBL98215 | N-(3-Methoxy-4-oxazol-5-yl-phenyl)-N...)
Show SMILES COc1cc(ccc1-c1cnco1)N=C(N)Nc1cccc(C)c1
Show InChI InChI=1S/C18H18N4O2/c1-12-4-3-5-13(8-12)21-18(19)22-14-6-7-15(16(9-14)23-2)17-10-20-11-24-17/h3-11H,1-2H3,(H3,19,21,22)
PDB
MMDB

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Similars

Article
PubMed
n/an/a>3.00E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
The compound was tested for it's in vitro inhibitor potency against inosine monophosphate dehydrogenase II (IMPDH II)


Bioorg Med Chem Lett 12: 2931-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00600-5
BindingDB Entry DOI: 10.7270/Q2SB454K
More data for this
Ligand-Target Pair