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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50119121   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50119121
PNG
(CHEMBL98322 | N''-cyano-N-[3-methoxy-4-(1,3-oxazol...)
Show SMILES COc1cc(NC(Nc2ccccn2)=NC#N)ccc1-c1cnco1
Show InChI InChI=1S/C17H14N6O2/c1-24-14-8-12(5-6-13(14)15-9-19-11-25-15)22-17(21-10-18)23-16-4-2-3-7-20-16/h2-9,11H,1H3,(H2,20,21,22,23)
PDB
MMDB

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Article
PubMed
n/an/a 340n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.


Bioorg Med Chem Lett 12: 2931-4 (2002)


Article DOI: 10.1016/s0960-894x(02)00600-5
BindingDB Entry DOI: 10.7270/Q2SB454K
More data for this
Ligand-Target Pair