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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50120001   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50120001
PNG
((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-methoxy-6-phen...)
Show SMILES COc1cc(nc(Nc2ccc(-c3cnco3)c(OC)c2)n1)-c1ccccc1
Show InChI InChI=1S/C21H18N4O3/c1-26-18-10-15(8-9-16(18)19-12-22-13-28-19)23-21-24-17(11-20(25-21)27-2)14-6-4-3-5-7-14/h3-13H,1-2H3,(H,23,24,25)
PDB
MMDB

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n/an/a 110n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Inosine Monophosphate Dehydrogenase II (IMPDH II)


Bioorg Med Chem Lett 12: 3125-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00641-8
BindingDB Entry DOI: 10.7270/Q2959GXF
More data for this
Ligand-Target Pair