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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50120533   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50120533
PNG
((3-Oxazol-5-yl-1H-indol-6-yl)-(5-phenyl-oxazol-2-y...)
Show SMILES N(c1ncc(o1)-c1ccccc1)c1ccc2c(c[nH]c2c1)-c1cnco1
Show InChI InChI=1S/C20H14N4O2/c1-2-4-13(5-3-1)18-11-23-20(26-18)24-14-6-7-15-16(9-22-17(15)8-14)19-10-21-12-25-19/h1-12,22H,(H,23,24)
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Article
PubMed
n/an/a 93n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzyme


Bioorg Med Chem Lett 13: 3557-60 (2003)


Article DOI: 10.1016/s0960-894x(03)00757-1
BindingDB Entry DOI: 10.7270/Q2J67G94
More data for this
Ligand-Target Pair
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50120533
PNG
((3-Oxazol-5-yl-1H-indol-6-yl)-(5-phenyl-oxazol-2-y...)
Show SMILES N(c1ncc(o1)-c1ccccc1)c1ccc2c(c[nH]c2c1)-c1cnco1
Show InChI InChI=1S/C20H14N4O2/c1-2-4-13(5-3-1)18-11-23-20(26-18)24-14-6-7-15-16(9-22-17(15)8-14)19-10-21-12-25-19/h1-12,22H,(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 93n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory concentration against Inosine-5'-monophosphate dehydrogenase 2 was determined


Bioorg Med Chem Lett 12: 3305-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00748-5
BindingDB Entry DOI: 10.7270/Q2Q81CD6
More data for this
Ligand-Target Pair