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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50123322   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50123322
PNG
(2-(3-Methanesulfonyl-phenyl)-7-methoxy-6-oxazol-5-...)
Show SMILES COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1cccc(c1)S(C)(=O)=O
Show InChI InChI=1S/C20H16N2O5S/c1-26-19-9-17-14(7-15(19)20-10-21-11-27-20)18(23)8-16(22-17)12-4-3-5-13(6-12)28(2,24)25/h3-11H,1-2H3,(H,22,23)
PDB
MMDB

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n/an/a 160n/an/an/an/an/an/a



Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibition of human inosine monophosphate dehydrogenase IMPDH II


Bioorg Med Chem Lett 13: 543-6 (2003)


Article DOI: 10.1016/s0960-894x(02)00944-7
BindingDB Entry DOI: 10.7270/Q2SJ1JZT
More data for this
Ligand-Target Pair