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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50123346   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50123346
PNG
(2-(3-Hydroxy-indan-5-yl)-7-methoxy-6-oxazol-5-yl-1...)
Show SMILES COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1ccc2CCC(O)c2c1
Show InChI InChI=1S/C22H18N2O4/c1-27-21-9-18-15(7-16(21)22-10-23-11-28-22)20(26)8-17(24-18)13-3-2-12-4-5-19(25)14(12)6-13/h2-3,6-11,19,25H,4-5H2,1H3,(H,24,26)
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MMDB

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Article
PubMed
n/an/a 28n/an/an/an/an/an/a



Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibitory activity against inosine monophosphate dehydrogenase IMPDH II


Bioorg Med Chem Lett 13: 547-51 (2003)


Article DOI: 10.1016/s0960-894x(02)00945-9
BindingDB Entry DOI: 10.7270/Q2NS0T7H
More data for this
Ligand-Target Pair