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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50123354   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50123354
PNG
(7-Methoxy-6-oxazol-5-yl-2-(3-pyrrolidin-1-yl-pheny...)
Show SMILES COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1cccc(c1)N1CCCC1
Show InChI InChI=1S/C23H21N3O3/c1-28-22-12-20-17(10-18(22)23-13-24-14-29-23)21(27)11-19(25-20)15-5-4-6-16(9-15)26-7-2-3-8-26/h4-6,9-14H,2-3,7-8H2,1H3,(H,25,27)
PDB
MMDB

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Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibitory activity against inosine monophosphate dehydrogenase IMPDH II


Bioorg Med Chem Lett 13: 547-51 (2003)


Article DOI: 10.1016/s0960-894x(02)00945-9
BindingDB Entry DOI: 10.7270/Q2NS0T7H
More data for this
Ligand-Target Pair